Clozapine for persistent aggressive behaviour or agitation in people with schizophrenia

Stable monotherapy with clozapine or olanzapine increases the incidence of diabetes mellitus in people with schizophrenia.

Risk factors: Participants diagnosed with diabetes mellitus or hospitalised with diabetic ketoacidosis were identified from the Department of Veterans Affairs and were predominantly older and male. Time to diagnosis and hospitalisation was modelled using the Cox proportional hazards models. Attributable risks of each outcome associated with different antipsychotics were calculated. The five ant...

Treatment interventions for people with aggressive behaviour and intellectual disability

Low Dose Celecoxib Combined with Clozapine for Treatment of Schizophrenia: A Double Blind Randomized Clinical Trial

Introduction: Higher levels of pro-inflammatory cytokines in schizophrenia have suggested that dysfunctions of the immune system may play a role in this disabling condition. The current study was performed to discover if low dose celecoxib combined with clozapine may improve symptoms of schizophrenia or not. Methods:<span...

Managing acutely aggressive or agitated people in a psychiatric setting: a survey in Lebanon

Background: Violent patients constitute 10% of all psychiatric admissions. Treatment options and clinical practice interventions vary across the globe and no survey of practice in a Middle Eastern setting exists. Surveying treatments in Lebanon will show treatment interventions used in this part of the world and, most importantly, provide the treatment options that could potentially be used for...

Participation of People With Schizophrenia in Everyday Life: Family’s Perspective

Objectives: People with chronic mental health condition like schizophrenia experience a lot of changes in their lives, in addition to their symptoms. The present study used a thematic analysis to explore the participation of people with schizophrenia in daily life from family’s perspective. It has uncovered some of the contributing factors in the everyday life participation of this group.  Met...